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Gobind Khorana Canada Excellence Research Chair in Precision Cancer Drug Design
Department of Biochemistry and Molecular Biology, Department of Urologic Sciences
Faculty of Medicine
COVID-19 Research Area(s)Vaccines & Treatments
Our research program is focused on exploring frontiers in structural biology and drug design using cryo electron microscopy (cryo-EM), with the central goal of accelerating the development of effective therapeutic agents.
The program is guided by two overarching themes:
- Drug design: A highly focused team effort to use high-resolution cryo-EM imaging of native protein complexes to design effective therapeutic agents targeting key drivers of diseases such as cancer, infectious diseases and brain disorders
- Technology development: An interdisciplinary approach towards developing next generation technologies in cryo-EM and related methods using automated workflows coupled with advanced image processing and machine learning.