Sriram Subramaniam

Gobind Khorana Canada Excellence Research Chair in Precision Cancer Drug Design

Department of Biochemistry and Molecular Biology, Department of Urologic Sciences

Faculty of Medicine

COVID-19 Research Area(s)

Research Specializations

Our research program is focused on exploring frontiers in structural biology and drug design using cryo electron microscopy (cryo-EM), with the central goal of accelerating the development of effective therapeutic agents. 

The program is guided by two overarching themes:

1. Drug design: A highly focused team effort to use high-resolution cryo-EM imaging of native protein complexes to design effective therapeutic agents targeting key drivers of diseases such as cancer, infectious diseases and brain disorders
2. Technology development: An interdisciplinary approach towards developing next generation technologies in cryo-EM and related methods using automated workflows coupled with advanced image processing and machine learning.